There are many reasons for recurrent implantation failures (RIF) and pregnancy losses, and for some expectant mothers, multiple factors may be at play. One of the key elements involved is the immune system.

The immune system plays a vital role in the formation and maintenance of a healthy pregnancy. Natural killer cells (NK), which are regulated by the immune system, can be excessively active in women with autoimmune diseases. When an embryo is implanted, women with autoimmune diseases may experience abnormal reactions in their natural killer cells. As a result, these cells may perceive the embryo as an invader, triggering an attack by the body. In such cases, the mother’s body may not accept the transferred embryo, leading to rejection, ultimately resulting in the failure of in vitro fertilization (IVF) treatment. Intralipid serum treatment aims to assist in balancing immune system irregularities that cause the inability of the embryo to implant in the uterus.

What is Intralipid Serum Treatment?

Intralipid serum therapy is a treatment method used to strengthen a woman’s immune system and enhance its ability to accept embryos and sustain pregnancy. This treatment is considered, particularly for women experiencing recurrent miscarriages or implantation failures.

Intralipid serum is a nutritious lipid emulsion containing components such as proteins and fats derived from soybeans, egg phospholipids, and glycerin. These substances are known to have positive effects in fortifying the immune system. The therapy aims to balance immune system irregularities, especially in women facing challenges in embryo acceptance, thereby improving the chances of successful pregnancy.

However, the treatment plan is individualized and determined after a personalized assessment, guided by a fertility specialist.

When Is Intralipid Serum Treatment Considered?

Intralipid serum therapy is typically considered in the following situations:

  • Recurrent Pregnancy Losses: When a woman has experienced three or more recurrent miscarriages, and/or
  • Recurrent Implantation Failures (RIF):In cases where embryos fail to attach to the uterus or pregnancy does not occur.
Frequently Asked Questions About Intralipid Serum

How Is the Intralipid Serum Treatment Applied?

Intralipid Serum treatment is typically combined with in vitro fertilization (IVF) or other assisted reproductive technologies.

The serum is administered to the expectant mother through the vein at specified intervals. Treatment typically starts before embryo transfer. After pregnancy is achieved, the administration may continue at regular intervals (usually once a week or every 2 weeks) up to the 8th week if deemed necessary. However, individual responses to the treatment may vary.

What are the Benefits of Using Intralipid Serum?

The primary role of Intralipid serum in IVF treatment is to balance the immune system. A healthy and well-balanced immune system can enhance the success rates of the treatment; however, the effectiveness may vary from one woman to another.

Are There Any Side Effects of Intralipid Serum?

It is known that there are no specific side effects associated with Intralipid serum treatment. However, some women may have allergies to certain components within the Intralipid serum, such as fats derived from soybeans, egg phospholipids, and glycerin. If there is a known allergy, the treatment should not be administered.

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