Egg retrieval, also called OPU (Oocyte Pick-Up), is one of the most exciting and important milestones in your IVF journey.

Understanding how to prepare for the procedure and care for yourself afterward can help maximize comfort, safety, and your chances of success.

In this guide, we explain everything you need to know about preparation, the procedure itself, and post-OPU recovery.

  • It may distort the pelvic anatomy by causing adhesions or cysts (endometriomas).
  • It can affect the quality of the eggs and ovarian reserve.
  • It may reduce implantation rates due to changes in the endometrium (the uterine lining).
  • Inflammation caused by the disease can negatively influence both eggs and sperm.

How to Prepare Before Egg Retrieval (OPU)

Trigger Injection

Once your doctor confirms that you are ready for egg retrieval, the trigger injection should be administered 35–36 hours before the procedure. Administering the injection exactly at the scheduled time is crucial for optimal results.

Fasting for Sedation

The egg retrieval is performed under sedation (anesthesia). Therefore, no food or drink should be consumed from midnight the night before the procedure. Depending on your procedure time, this corresponds to approximately 6–8 hours of fasting.

Anesthesia Duration

The anesthesia typically lasts 15–20 minutes, allowing for a safe and comfortable procedure.

Sexual Activity During Egg Retrieval Preparation
  • Before starting ovarian stimulation injections: Sexual activity is allowed.
  • During ovarian stimulation: It is recommended to avoid sexual intercourse until embryo transfer. During stimulation, ovaries enlarge and become sensitive, which may cause discomfort, pain, ovarian torsion, or premature ovulation. Eggs may be affected by sexual activity, potentially reducing procedure efficiency.
  • After embryo transfer: From transfer until the pregnancy test, sexual activity should be avoided to support implantation.
Pool, Sea, and High Heat Environments
  • Swimming: Avoid pools or the sea from the start of stimulation injections until recovery after the procedure to minimize infection risk.
  • High heat environments: Sauna, Turkish bath, and jacuzzis are not recommended from the start of stimulation injections until the day of OPU.
What to Keep in Mind on Your Egg Retrieval Day
  • Fasting and Hydration: It is recommended to avoid eating, drinking, chewing gum, and smoking 6–8 hours before the procedure. Ensure your bladder is empty to make the process easier.
  • Hygiene and Cosmetics: A shower on the morning of the procedure is sufficient. Please refrain from using perfume, deodorant, creams, makeup, nail polish, or artificial nails.
  • Medication: Avoid aspirin or other blood-thinning medications unless instructed by your doctor.
  • Personal Items: It is advised to remove all jewelry and metal accessories.
  • Night Before: Try to avoid foods that may cause gas to minimize discomfort.
  • Trigger Injection: Administer the injection exactly at the scheduled time as advised by your medical team.
  • Genital Area Hygiene: Shaving or trimming 1–2 days before is recommended. On the day of OPU, a warm shower is sufficient. Avoid soaps, vaginal creams, or perfumed products unless prescribed by your doctor.
Partner Guidelines

On egg retrieval day, a sperm sample will be collected. For best results, partners are advised to refrain from sexual activity for 3 days prior to maintain sperm quality.

After Egg Retrieval: Recovery Guidelines

Rest and Activity

Avoid driving for 24 hours and refrain from heavy physical activity, exercise, or lifting heavy objects.

Travel

Plan any travel at least 1 day after the procedure to ensure proper recovery.

Nutrition and Fluids

Unless instructed otherwise, resume your normal diet. Drink plenty of fluids and avoid gas-producing foods, alcohol, and smoking.

Hygiene and Health

A warm shower is safe after the procedure. Avoid swimming pools, the sea, and jacuzzis due to infection risk.

Medication

Take painkillers (e.g., paracetamol) and IVF support medications (e.g., progesterone) as prescribed.

Normal Symptoms

After the procedure, mild lower abdominal or pelvic discomfort, bloating, light spotting, temporary breast tenderness, fatigue, or mild cramping are normal. These symptoms usually improve within 1–2 days.

When to Contact Your Doctor

Contact your doctor promptly if you experience:

  • Severe or persistent abdominal pain
  • High fever
  • Foul-smelling vaginal discharge
  • Excessive bleeding (bright red)
  • Shortness of breath
Hi, How Can We Help You?
özkan aydın
1 week ago
V S
2 weeks ago
I cannot thank Cyprus IVF Hospital enough for the incredible care and support I received throughout my IVF journey. A very special thank you to Rojda, our personal nurse, who has been absolutely amazing from start to finish. Rojda was always supportive, helpful, caring, and compassionate during such an emotional and difficult time. Her communication was always clear, fast, and reassuring, and she genuinely showed so much love and care every step of the way. She guided me through everything with patience and kindness, which made such a huge difference to my experience. I am truly so thankful for all of her help and support. Thank you so much Rojda and thank you Cyprus IVF Hospital for making this journey feel so much less overwhelming. Highly recommended!
Response from the owner:Thank you so much for your kind words and for taking the time to share your experience.❤️ We are truly delighted to hear that you felt supported throughout your IVF journey. We understand how emotional and challenging fertility treatment can be, and it means a great deal to know that we were able to provide the care, guidance, and reassurance you needed along the way.💖 Thank you for placing your trust in Cyprus IVF Hospital. We wish you all the very best and look forward to hearing more wonderful news from you in the future. Warm regards, Cyprus IVF Hospital Patient Experience Department
maria ruggiero
1 month ago
Very good experience. I really recommend the clinic.
Response from the owner:Thank you so much for your kind words and for taking the time to share your experience.❤️ Cyprus IVF Hospital Patient Experience Department
İlayda Aydilek
1 month ago
Daha önce başka bir merkezde denedikten sonra burası ile yolum kesişti. İyi ki de kesişmiş çıktığımız bu zorlu süreci güler yüzlü ekibiyle bana güvende ve emin ellerde olduğumu hissettiren ve başta selen hanım ve ekibi 💕 gönül rahatlığıyla güvenebileceğiniz tertemiz bir hastane deneyimli kadrosu ile sayelerinde bizimde evlat hasretimiz sona erecek inşallah 🙏🏻 herkese sonsuz teşekkürler.
gözde çaplı
2 months ago
Güzel aldığımız sonuclardan sonra öncelıkle doktorlarıma ve meryem hanıma çok teşekkür ediyorum bu sürecde benımle en özel şekilde ve saat farketmeden sorularımı cevaplayıp en iyi şekılde destek olundu herşey için özellıkle meryem hanıma tüm katkılarından kaynaklı ve özel ilgisinden tekrardan teşekkür ederim iyi ki varsınız mucizeme kavuşmak için şimdiden sabırsızım
Response from the owner:Değerli yorumunuz ve güzel sözleriniz için çok teşekkür ederiz. 💙 Süreç boyunca kendinizi desteklenmiş ve güvende hissettiğinizi duymak bizim için büyük mutluluk. Mucizenize kavuşma yolunda size eşlik edebilmiş olmaktan onur duyuyoruz. Size sağlıklı, huzurlu ve mutluluk dolu bir hamilelik süreci diliyoruz. ❤️ Kıbrıs Tüp Bebek Hastanesi Hasta Deneyimi Departmanı
TeamCP fitness
2 months ago
I can not thank Chaimaa Quadini and the IVF team Enough. From start to finish they have supported me through absolutely everything. Chaimaa has been my best friend throughout of this and I’m not to sure what I would have done without here. Whatever day or time she always is there for m. I have had a positive test and I’m absolutely over the moon. I will be back with baby 💕
Dalala Bhari
2 months ago
I would like to express my deepest gratitude to my coordinator, Damla, who has been an incredible support throughout my journey. She is truly the face of this center: flawless, always attentive, and exceptionally professional. Thanks to her proactivity and constant care, she created an environment of total trust, which is so essential in this process. She is sincerely dedicated to her patients' well-being, and that makes all the difference. I cannot recommend this clinic highly enough. If you are hesitating between two clinics, go for this one: Damla’s quality of care is the deciding factor that will make you feel serene and fully supported.
Parfloral
3 months ago
Thank you Dr İçten for making our dreams come true. The clinic is a professional place with latest technologies and we felt well cared for.
Helin
3 months ago
Öneriler sayesinde merkezle tanıştım. Selen hemşire gece gündüz demedi aklıma takılan ne varsa hepsine cevap verdi sıkılmadan☺️ sonra merkeze gidip tanıştım ve aynı ilgi orda da devam etti. Bu işlerde en önemli şeylerden biri enerjinin tutması. Doktordan, embriyoloğa herkes çok ilgiliydi ve sonucumuz pozitif oldu. Çokkkk teşekkür ediyorum.
Dervise Sadikel
3 months ago