Donors

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DONORS

  • Must be between the ages of 20 and 32
  • Should not have any marked physical characteristics such as an unusual noise that might distinguish her.
  • Donors are selected according to the recipient's race, colour and blood type ,donor's intelligence level should be average or above average
  • Must not have any physical restrictions against procedures such as controlled ovarian hyperstimulation and egg collection
  • A person who has known genetic diseases in the family or has lost a baby for unexplained reasons cannot be accepted in the program as a donor.
Some or all of these tests may be required
  • Kan grubu
  • Hepatit B ve C
  • HIV (AIDS)
  • Frengi
  • Hemoglobin elektroforezi (Talasemi)
  • Mikoplazma, Klamidya, CMV, Toksoplazmoz, Listeria
  • Kromozomal Karyotipleme
  • Kistik fibroz
  • Hemofili , Ailesel Akdeniz Ateşi (FMF) M964V mutasyonu, Fenilketonüri

Once donors are accepted into the program, they are placed into categories based on the criteria listed below. These criteria are used to make the closest match between the donor and recipient.

  1. Height
  2. Weight
  3. Blood Type
  4. Race
  5. Skin colour
  6. Eye colour
  7. Hair Color
  8. Education status

Egg collection does not reduce the oocytes available to the woman. The procedure does not affect the donor’s fertility and age of menopause onset. Her chances of achieving pregnancy will be no different after she donates her eggs.

Briefly, the donor goes through two main steps. The first prepares the ovaries to stimulate increased egg production, and the second is collecting those eggs that develop. The woman will start the drug regimen on the second or third day of menstruation. The eggs will be collected after approximately 8-12 days of stimulation. Egg collection marks the end of the donor’s role in the process. Her eggs will be inseminated by the sperm obtained from the recipient’s husband, and the resulting embryos will be transferred to the recipient’s uterus.

Preparation of the recipient:

If the recipient menstruates regularly, there are two methods to prepare her uterus. Either the recipient’s cycle is synchronised to that of the donor by using a combination of hormonal supplements, or they temporarily suppress the recipient’s ovulation. Doctors usually use GnRH analogue drug type for this purpose. After the woman has her period, she starts taking estrogen hormone orally; later, Progesterone is added on the day the eggs are collected. This way, the endometrium (uterine lining) acquires the necessary thickness for the embryo to implant.

Preliminary tests done before the procedure are summarised below.

  • A mock transfer with the same type of catheter used to transfer the embryos. Menopausal women, in particular, may have a narrow or deformed cervix. The cervix can be dilated under anaesthesia if necessary.
  • Gynecological ultrasonography
  • A pelvic exam where the doctor may take a pap smear or order a colposcopy for a more detailed examination.
  • Hysteroscopy (if the clinician cannot get a clear view of the uterine lining through ultrasonography)
  • Preparation of the endometrium (the uterine lining that is shed every month) using drugs. For a successful pregnancy to occur, the recipient's endometrial thickness should reach at least 8mm.

Our centre may run the following tests on the recipient couple:

Recipient

  • Blood type
  • Panel of pre-pregnancy blood tests
  • Hepatitis B, C
  • HIV (AIDS)
  • Hemoglobin electrophoresis
  • Mycoplasma
  • Chlamydia
  • CMV
  • Toxoplasmosis
  • Syphilis
  • Herpes
  • Rubella

Husband of recipient

  • Blood type
  • Panel of metabolic blood tests
  • Hepatit B, C
  • HIV (AIDS)
  • Hemoglobin electrophoresis
  • Sperm count
  • Syphilis
  • Cystic Fibrosis
  • Y Chromosome microdeletion test
  • Chromosome analysis (karyotype)